Drug Literature Evaluation and Informatics I Case Solution And Analysis, HBR Case Study Solution & Analysis of Harvard Case Studies

Part 2: Literature Search

Directions: Type your answers for Part 2(questions 1- 4 of 4) directly into this document below each respective question. Please use 12-point font, Times New Roman and single space the text. Refer to the Excel document for your assigned secondary database, to complete this portion of the assignment. Your search will be based upon the clinical case scenario assigned in Part 1. This section of the assignment will be evaluated, using the Individual WrittenAssignment Part 2: Literature Search Evaluation Form.

Identify and list one clinical question from the case scenario that can best be searched for in a secondary resource. Underline the major concepts of the question that will be used for your literature search. (Hint: the major concepts of the question should reflect the PICO components of the question.)

P: 57-year-old man, who had heart attack

I: Ticagrelor

C: acetylsalicylic acid

O:Prevention of the future heart attack

Question: Is using Ticagrelor in patients with prior heart attack is effective, as compared to the aspirin in the prevention of the future heart attack?

Drug Literature Evaluation and Informatics I Harvard Case Solution & Analysis

Complete a column for each major concept in your search. Add additional columns as needed.

	Concept 1: Heart attack	Concept 2: Ticagrelor	Concept 3: Aspirin	Concept 4: Prevention of future heart attack
MeSH term, Supplementary concept, or EMTREE term	MYOCARDIUM (MeSH term)	Ticagrelor (Supplementary concept)	Aspirin (Supplementary concept)	None (Keyword only)
Synonyms	Cardiovascular disease congestive heart failure cardiac arrest myocardial infarction	None	Morphine Ointment Tranquilizer Sedative analgesic	N/A
Narrow terms	Heart Disease	None	None	N/A
Broader terms	Cardiovascular Disease	None	None	N/A

Clinical Trial Article

Bonaca M, Bhatt D, Steg P et al. Ischaemic risk and efficacy of ticagrelor, in relation to time from P2Y12inhibitor withdrawal in patients with prior myocardial infarction: insights from PEGASUS-TIMI 54. European Heart Journal. 2015; 37(14):1133-1142. doi:10.1093/eurheartj/ehv531.

PubMed (1996- April 3, 2017) was searched, using the search engine of the US national library.With the help MeSH Medical subject headings search engine, the main important terms included such as ticagrelor and aspirin in the heart patients, effectiveness of the ticagrelor and aspirin in the heart patients, and use of the ticagrelor and aspirin in prevention of the heart attack, continuously for more than 1 year.

Meanwhile, the search was limited to the randomized, controlled trials and humans. Indeed, many articles were found to be associated with our clinical question, nothing was excluded. On the other hand, articles included all major problems in and objective of the paper.Meanwhile almost all articles looked to address the key problems and objectives of the scenario questions. Because, all articles provided the evidence based research that supported statement of the scenario.

Part 3: Literature Summary

Directions: Type your answers for Part 3A (questions 1- 11 of 11) and Part 3B directly into this document below each respective section. Please use 12-point font, Times New Roman, and single space the text. Refer to the Excel document for your assigned literature citation to complete this portion of the assignment. This section of the assignment will be evaluated using the Individual Written Assignment Part 3: Literature Summary Evaluation Form.........................

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